Kardiogen Test Polygenic Risk Score Test For Heart Problem Diagnosis, How To Know Heart Disease Risk You will be able to know easily with this test, know in detail



Until about a decade ago, heart diseases were known as a problem with aging, although now younger people are also found to be victims of it. Cardiovascular disease (CVD) is the leading cause of increasing mortality worldwide. According to the World Health Organization (WHO), India alone accounts for 20 per cent of youth deaths due to heart diseases worldwide.

In recent years, many celebrities have died of heart attacks at a young age. Health experts say that since the risk of heart diseases is increasing in people of all ages with time, there is a need to take special care about it.

Symptoms of CVD usually appear only when damage has already begun to the arteries that supply blood to the heart. There can be many reasons for this, including lifestyle disturbances, nutritional deficiencies in diet, high blood pressure, smoking, and obesity being seen as major risk factors. To find out the risk of heart diseases, a team of scientists has found out about such a method of genetic sequencing, on the basis of which it can be estimated that how high the risk of developing heart diseases is in you. Let us know about this.

heart disease risk screening

With the invention of Next Generation Sequencing, complete genetic sequencing can now be performed to test for changes in a patient’s genes. This technique helps to understand the genetic basis of common diseases such as CVD. Diseases such as CVD, by their nature, are polygenic (the result of multiple genes). For this, the method of polygenic risk score (PRS) is used to find out the genetic risk of a person for a particular disease. That is, now it can be estimated that how much you are genetically prone to heart diseases?

What is a Polygenic Risk Score?

The polygenic risk score integrates multiple changes in the human genome. It has the ability to detect people who are at risk of developing diseases like heart disease. A recent study conducted at several centers has shown that South Asian people are at higher risk of coronary artery diseases. In this, the researchers found that Indians are three times more likely to have diseases related to the heart and blood vessels as compared to other countries.

Cardiogen test will reveal the risk of heart diseases

The Cardiogen Test, released by MedGenome’s GeneSense, is a test to determine whether a person’s genes are at risk for future cardiovascular diseases. It integrates over 6 million sites in a human’s DNA and tells them how much they are at risk of heart attacks, explains Dr. Vedam Ramprasad (Scientist and CEO, Med Genome Lab).

This is called the Cardiogen Risk Score (KRS), which can predict the risk of heart disease with an accuracy of 90 percent. On the basis of KRS, it can be identified which person is more prone to heart attack in future, who has mild attack and who is at average risk of it.

Know your risk in advance

Experts say that knowing your risk factors on the basis of this test can be avoided. This will also help in reducing the risk of death due to heart diseases. However, the risk of developing heart diseases also depends on clinical factors, such as blood pressure, cholesterol and smoking levels. The combination of clinical risk and KRS suggests the patient’s potential risk of heart disease. Patients can avail the facility of Cardiogen test sitting at home. Cardiogen test can be done in one go by people above 18 years of age to find out the risk of heart diseases in future.


Note: This article has been prepared on the basis of medical reports and suggestions from health experts.

Disclaimer: All the articles published in the health and fitness category of Amar Ujala are prepared on the basis of interaction with doctors, experts and academic institutions. The facts and information mentioned in the article have been verified and verified by the professional journalists of Amar Ujala. All instructions have been followed while preparing this article. The related article has been prepared to increase the knowledge and awareness of the reader. Amar Ujala does not claim nor take any responsibility for the information and information provided in the article. Consult your doctor for more details about the related disease mentioned in the above article.



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